 |
Case Series
Ocular manifestations and treatment course of monkeypox virus in two males with acquired immunodeficiency syndrome
1 MD, Resident, Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN, USA
2 MD, Fellow, Department of Ophthalmology, University of Colorado, Aurora, CO, USA
3 BS, Medical Student, Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN, USA
4 MD, PhD, Resident, Department of Ophthalmology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN, USA
5 MD, Attending, Department of Ophthalmology, VA, Memphis, TN, USA
Address correspondence to:
Nikolas Hopkins
930 Madison Avenue, Suite 460, Memphis, TN 38103,
USA
Message to Corresponding Author
Article ID: 100042Z17NP2024
Access full text article on other devices
Access PDF of article on other devices
How to cite this article
Hopkins N, Tang A, Hilliard G, Liu J, Louie E, Kwak HG, Partal A. Ocular manifestations and treatment course of monkeypox virus in two males with acquired immunodeficiency syndrome. J Case Rep Images Opthalmol 2024;7(2):3–8.ABSTRACT
Introduction: Mpox (formerly monkeypox) is a previously endemic virus that has become a global concern.
Case Report: In this case series, we present two cases of ocular mpox in men with acquired immunodeficiency syndrome (AIDS), highlighting their clinical presentation, diagnosis, and management. Treatment involved the use of antiviral medications, tecovirimat and ganciclovir, based on limited existing data and recommendations from the Center for Disease Control (CDC).
Conclusion: These cases highlight the variability in presentation among AIDS patients with extensive corneal and conjunctival involvement and the potential for immune reconstitution inflammatory syndrome upon re-initiation of anti-retroviral therapy during active mpox infection. These cases emphasize the importance of early recognition, involvement of ophthalmology, and a multidisciplinary approach to prevent vision-threatening complications.
Keywords: AIDS, HIV, Monkeypox, Mpox, Ocular mpox, Ophthalmology, Orthopoxvirus, Tecovirimat
SUPPORTING INFORMATION
Author Contributions
Nikolas Hopkins - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Anthony Tang - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Grant Hilliard - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Jillian Liu - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Emily Louie - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Hakyong Gloria Kwak - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Andreea Partal - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2024 Nikolas Hopkins et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
