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Case Report
A rare case of isolated periorbital inflammation due to demodex folliculitis
1 Department of Ophthalmology and Visual Sciences, Yale University, 40 Temple St., New Haven, CT 06510, USA
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Brittany Perzia
Department of Ophthalmology and Visual Sciences, Yale University, 40 Temple St., New Haven, CT 06510,
USA
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Article ID: 100035Z17BP2023
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Perzia B, Theotoka D, Spadaro J, Habib L. A rare case of isolated periorbital inflammation due to demodex folliculitis. J Case Rep Images Opthalmol 2023;6(1):1– 4.ABSTRACT
Introduction: We report an unusual case of demodex folliculitis presenting as isolated bilateral periorbital inflammation without other classical symptoms of demodicosis.
Case Report: A 46-year-old female presented with bilateral eyelid edema without erythema for two years. She denied pain, itching, or rashes. Her ocular exam was unrevealing and without evidence of blepharitis or meibomian gland dysfunction. Inflammatory workup, including thyroid antibodies, was negative. Computed tomography (CT) orbits showed no orbital masses. She was trialed on oral doxycycline therapy with no improvement. Subsequent skin tissue biopsy from upper lid blepharoplasty was consistent with Demodex folliculitis, and the patient’s symptoms significantly improved after initiation of terpinen-4-ol (T40) tea tree oil eyelid wipes.
Conclusion: This case suggests that Demodex folliculitis should be included in the differential diagnosis for bilateral periorbital inflammation, even in the absence of the typical signs and symptoms of ocular demodicosis.
Keywords: Blepharitis, Demodex folliculitis, Inflammation
SUPPORTING INFORMATION
Acknowledgments
Dr. John Sinard, MD PhD for histopathological analysis of biopsy specimens.
Author ContributionsBrittany Perzia - Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Despoina Theotoka - Acquisition of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Jane Spadaro - Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Larissa Habib - Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2023 Brittany Perzia et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
