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Case Report
Unilateral transient subretinal hyperreflective material in multiple evanescent white dot syndrome: A case report
1 Resident, MD, Department of Ophthalmology, Ghent University Hospital, Ghent, East Flanders, Belgium
2 Consultant, MD, Department of Ophthalmology, AZ Sint-Jan, Bruges, West Flanders, Belgium
Address correspondence to:
Jean-Baptiste Frédéric Willemot
MD, Department of Ophthalmology, Ghent University Hospital, Corneel Heymanslaan 10, 9000 Ghent, East Flanders,
Belgium
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Article ID: 100015Z17JW2020
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How to cite this article
Willemot JBF, Vandelanotte S. Unilateral transient subretinal hyperreflective material in multiple evanescent white dot syndrome: A case report. J Case Rep Images Opthalmol 2020;3:10.5348/100015Z17JW2020CR.ABSTRACT
Introduction: The term subretinal hyperreflective material refers to the hyperreflective material located external to the retina and internal to the retinal pigment epithelium on optical coherence tomography. Multiple evanescent white dot syndrome is a white dot syndrome characterized by transient multifocal yellow-white fundus lesions. The case of a 77-year-old female with the diagnosis of multiple evanescent white dot syndrome and an unusual and transient unilateral subretinal hyperreflective material on optical coherence tomography is reported. Subretinal hyperreflective material may be observed in multiple evanescent white dot syndrome as well as many other retinal diseases.
Case Report: A 77-year-old female presented with a history of photopsia and a decreased eyesight in the right eye for the past two weeks. Fundus examination revealed a yellow macular lesion and multiple subretinal deposits in the midperiphery in the right eye. There was a diffuse subretinal hyperreflective deposition on optical coherence tomography. An extensive work-up was done to exclude systemic causes. She was diagnosed with multiple evanescent white dot syndrome as there was a spontaneous and complete resolution of the funduscopic lesions and the optical coherence tomography findings within a four weeks’ time span.
Conclusion: Subretinal hyperreflective material is due to a focal or generalized dysfunction of the retinal pigment epithelium and can be present in various retinal disorders, such as multiple evanescent white dot syndrome. The thick and extensive layer of subretinal deposition is an unusual finding in multiple evanescent white dot syndrome and reflects an extensive transient dysfunction of the retinal pigment epithelium in this disease.
Keywords: Adult-onset vitelliform macular dystrophy, Age-related macular degeneration, Multiple evanescent white dot syndrome, Retinal pigment epithelium, Subretinal hyperreflective material
SUPPORTING INFORMATION
Author Contributions
Jean-Baptiste Frédéric Willemot - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Sylvie Vandelanotte - Analysis of data, Interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2020 Jean-Baptiste Frédéric Willemot et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
